Neuromet Tablet 500mcg (Mecobalamin)
Martin Dow Marker LtdDRAP reg. 020991
We sell this without asking for a prescription
Same day or next day in Karachi, Lahore, Islamabad, Rawalpindi for orders confirmed before 6pm. Tracked courier, 2 to 4 working days everywhere else. Delivery Rs 250 in Rawalpindi and Islamabad, Rs 300 everywhere else, cash on delivery. Delivery details
Prices in PKR, checked 23 October 2026.
What Neuromet is
Neuromet (mecobalamin 500 mcg, a form of vitamin B12) is used for nerve damage in the hands and feet (peripheral neuropathy), including diabetic neuropathy, and for vitamin B12 deficiency and the anaemias it causes, according to Martin Dow Marker’s Pakistani leaflet for Neuromet Tablets. No Pakistani document we could find states its condition of sale, and we sell it without a prescription.
- Registered with DRAP under number 020991. (DRAP registry entry).
- Made by Martin Dow Marker Ltd, Quetta, which DRAP’s record lists as the registration holder since 2018.
- If it doesn’t help, don’t keep taking it for months: the Japanese package insert for Methycobal tablets (Eisai, revised April 2023) says that if no effect is seen, it should not be used aimlessly over a period of months.
- DRAP notifies no price for Neuromet: every pack is de-controlled, and the price index has no entry.
What is in each tablet
One active ingredient, from the label claim in DRAP’s registry: “Each sugar-coated tablet contains: Mecobalamin.......500 mcg (JP Specs)”.
| Ingredient | Amount per tablet |
|---|---|
| Mecobalamin (methylcobalamin, a form of vitamin B12) | 500 mcg |
“JP Specs” refers to the Japanese Pharmacopoeia standard, which DRAP told all holders of mecobalamin tablet registrations to follow in October 2025 (DRAP notification).
What it is used for
Martin Dow Marker’s leaflet lists a broader set of uses than Japan’s label for the same medicine.
| Label | Uses |
|---|---|
| Pakistan, Martin Dow Marker leaflet | Peripheral neuropathy (for example diabetic, alcoholic and uraemic neuropathy); drug-induced neuropathy; neurological disease and ageing; symptoms of vitamin B12 deficiency; prolonged inadequate or incorrect nutrition, such as a strict vegetarian diet; malabsorption from a lack of intrinsic factor; megaloblastic, macrocytic and pernicious anaemia; and congenital disorders of vitamin B12 transport. |
| Japan, Methycobal (Eisai) | Peripheral neuropathy only. |
For B12 deficiency anaemia, the NHS says it is usually treated with injections of vitamin B12 (hydroxocobalamin), and that where the cause is a lack of B12 in the diet, daily B12 tablets may be advised. A doctor should find the cause first.
How to take it
The maker’s leaflet gives adults three doses a day, for peripheral neuropathy and for its other uses, adding “or as prescribed by the physician” for the other uses, so how much to take is for your doctor to decide.
- If there is no improvement, ask your doctor before carrying on: the Japanese label says it should not be used aimlessly over months when no effect is seen.
- Take the tablet out of the blister before swallowing it: the Japanese label warns that a swallowed blister piece can pierce the food pipe.
- Keep it away from light, heat and moisture, below 30 °C, as the leaflet says: the Japanese label adds that light lowers the tablet’s content and moisture can turn it reddish.
Who should not take it, or should ask a doctor first
From Martin Dow Marker’s Pakistani leaflet for Neuromet Tablets unless the Japanese label is named.
- Must not take it: anyone allergic to Neuromet or its ingredients, or sensitive or allergic to cobalamin or cobalt.
- People who handle mercury or its compounds at work: the leaflet says prolonged use is not recommended, and the Japanese label says long-term high doses are best avoided in such workers.
- Children: the leaflet gives an adult regimen only, and the Japanese label says no clinical trials were done in children. Ask a doctor for a child.
Other medicines and alcohol
Tell your doctor or pharmacist about every medicine you take. Martin Dow Marker’s Pakistani leaflet for Neuromet Tablets names these in particular.
| Medicine or other | What the source says | Source |
|---|---|---|
| Metformin (for diabetes) | What the source says: Named by the leaflet. The UK medicines regulator, the MHRA, says low vitamin B12 is a common side effect of metformin and advises checking B12 levels in people on metformin with symptoms of deficiency. | Source: Leaflet; MHRA, 2022 |
| Stomach-acid medicines (“anti-ulcerants”): proton pump inhibitors and H2 blockers | What the source says: Named by the leaflet. | Source: Leaflet |
| Para-aminosalicylic acid (for tuberculosis); metronidazole, chloramphenicol and neomycin (antibiotics); contraceptives; colchicine; cobalt; some resins | What the source says: Named by the leaflet. | Source: Leaflet |
| Nicotine, nitrous oxide, phenytoin, phenobarbital; folic acid and potassium | What the source says: Named by the leaflet. | Source: Leaflet |
| Alcohol | What the source says: Heavy drinking for more than two weeks can reduce B12 absorption; the leaflet advises no alcohol while taking Neuromet. | Source: Leaflet |
Folic acid: the NHS says folic acid doses higher than 1 mg can mask the symptoms of vitamin B12 deficiency.
Pregnancy and breastfeeding
The maker’s leaflet says no risks have become known with use in pregnancy at the recommended dosage, and that it passes into breast milk, though the risk of overdose for the baby is not known.
The Japanese label has no pregnancy section. If you are pregnant or breastfeeding, ask your doctor before taking it.
Side effects
The maker’s leaflet says to contact your doctor at once if loss of appetite, nausea, vomiting or diarrhoea happen with the tablets.
| How often | Side effects |
|---|---|
| 0.1% to under 5% (Japan) | Loss of appetite, nausea and vomiting, diarrhoea. |
| Under 0.1% (Japan) | Rash. |
Driving: the leaflet says it should not affect your ability to drive or use machines.
Neuromet SL is a different product
Neuromet SL is a mecobalamin tablet that dissolves under the tongue, in 500, 1000 and 2000 mcg, made by Novamed Healthcare for Martin Dow Marker. Its leaflet calls it a “Nutritional supplement - not for tretment of any disease.”
There is no 1000 mcg Neuromet tablet to swallow: 1000 mcg is Neuromet SL only. We did not find Neuromet SL in DRAP’s registered drugs index. This page sells Neuromet Tablets 500 mcg, not Neuromet SL.
Checking your pack is genuine
As of 22 October 2026, no DRAP alert names Neuromet. DRAP has issued alerts on other companies’ mecobalamin products, mostly injections.
- Check that the batch number on the carton matches the batch number on the blister inside, and that the pack is sealed.
We buy only from authorised distributors, and check the batch and expiry on every item before it is packed.
Information as of 22 October 2026. DRAP publishes new alerts on dra.gov.pk.
Returns and replacements
Medicines and supplements can’t be returned once they have left our pharmacy.
- Returned medicine can never go back into saleable stock. That is a safety rule, not a commercial one.
- If an item arrives damaged or wrong, tell us on WhatsApp within 24 hours and we replace it. That is us fixing our mistake, not a return.
- Anything that arrives expired or within a month of expiry we replace or refund, your choice, with no time limit.
Frequently asked questions
What is Neuromet tablet used for?
Neuromet contains mecobalamin, a form of vitamin B12. Martin Dow Marker’s leaflet lists peripheral neuropathy (nerve damage, for example from diabetes or alcohol), drug-induced neuropathy, symptoms of vitamin B12 deficiency, poor absorption of B12 and the anaemias B12 deficiency causes. Japan’s label for the same medicine lists peripheral neuropathy only.
How long does this medication take to work?
The labels we read give no time to expect an effect. The Japanese label says that if no effect is seen, it should not be used aimlessly over a period of months, so ask your doctor if you notice no change.
Does this medication make you sleepy?
Sleepiness is not among the side effects the maker’s leaflet or the Japanese label lists, and the leaflet says it should not affect your ability to drive or use machines.
Can I take this medication everyday?
The leaflet’s adult regimen is daily, three times a day, and adds “or as prescribed by the physician”, so your doctor sets how much and for how long. The Japanese label says not to keep taking it for months if it isn’t helping.
Is Neuromet SL the same as Neuromet tablets?
No. Neuromet SL dissolves under the tongue, comes in 500, 1000 and 2000 mcg, and its leaflet calls it a nutritional supplement, not for the treatment of any disease. Neuromet Tablets 500 mcg are a registered medicine, DRAP registration 020991. This page sells the tablets.
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Questions about Neuromet Tablet 500mcg (Mecobalamin)?
Send your question on WhatsApp and a pharmacist will come back to you.
Written by the ePharmacyy pharmacy team.
Last checked against the sources below on
DRAP registration
- Neuromet Tablet (020991), Martin Dow Marker Limited. DRAP’s registry shows: Provisionally Active, “Not Verified”.
DRAP publishes no definition of this verification flag, so we can’t tell you what it means. We searched DRAP’s website for “Neuromet”, “mecobalamin” and “methylcobalamin” on 22 October 2026 and found no alert naming Neuromet or Martin Dow; the mecobalamin results were alerts on other companies’ products, mostly injections, and notices on how mecobalamin products must be made and tested. When we tested it, the search did not find a word that appears only inside an alert’s attached PDF, so an alert that names a product only in its PDF may not show up. DRAP describes its registered products index as a provisional list that “cannot be used as a reference for any purpose”. Checked against the registry on .
Sources
- DRAP registered products: Neuromet Tablet, registration 020991
- DRAP notified price index (no entry for Neuromet or mecobalamin)
- DRAP: product specification of mecobalamin / methylcobalamin tablet, 22 October 2025 (PDF)
- Martin Dow Marker: Neuromet Tablets/Injection leaflet, Pakistan (item 13002772, image PDF)
- Martin Dow Marker: Neuromet SL Tablets leaflet, Pakistan (image PDF)
- PMDA (Japan): Methycobal tablets package insert, Eisai, revised April 2023 (in Japanese)
- MHRA Drug Safety Update: metformin and reduced vitamin B12 levels, 20 June 2022
- NHS: vitamin B12 or folate deficiency anaemia, treatment
- NHS: B vitamins and folic acid