Loprin Tablet 75mg and 150mg (Aspirin)
Highnoon Laboratories LtdDRAP reg. 014900
Prescription required
Highnoon’s Pakistani leaflet says Loprin is to be sold on prescription only, so we dispense it on prescription.
Same day or next day in Karachi, Lahore, Islamabad, Rawalpindi for orders confirmed before 6pm. Tracked courier, 2 to 4 working days everywhere else. Delivery Rs 250 in Rawalpindi and Islamabad, Rs 300 everywhere else, cash on delivery. Delivery details
Prices in PKR, checked 23 October 2026.
What Loprin is
Loprin (low-dose enteric-coated aspirin, 75 mg or 150 mg) stops blood platelets from clumping and is used to prevent heart attacks and strokes in people with heart or circulation disease (secondary prevention), in angina and heart attack, after a transient ischaemic attack or stroke, and after coronary bypass surgery, according to Highnoon’s Pakistani leaflet for Loprin. The leaflet says it is to be sold on prescription only, so we dispense it on prescription.
- Loprin 75mg is DRAP reg. 014900 (DRAP registry entry); the 150mg tablet is DRAP reg. 013127. DRAP records both as gastro-resistant tablets.
- Made by Highnoon Laboratories in Lahore: Highnoon’s own product page lists Loprin as enteric-coated aspirin in 75 mg and 150 mg tablets, in packs of 30.
- Not a painkiller: the Pakistani leaflet says aspirin 75 mg is not suitable for use against pain, fever or inflammation.
- Before starting long-term aspirin for heart or stroke prevention, the leaflet says to consult your doctor about the benefits and risks for you.
- DRAP controls Loprin’s price: its price index sets Rs 87.73 for 30 tablets of 75 mg and Rs 115.64 for 30 of 150 mg, effective 27 July 2026, and we charge less.
What is in each tablet
One active ingredient, aspirin, in an enteric-coated tablet, from the label claims in DRAP’s registry.
| Tablet | Ingredient | Amount per tablet |
|---|---|---|
| Loprin 75mg (DRAP reg. 014900) | Ingredient: Aspirin | Amount per tablet: 75 mg |
| Loprin 150mg (DRAP reg. 013127) | Ingredient: Aspirin | Amount per tablet: 150 mg |
The Pakistani leaflet says Aspirin 75 mg contains lactose.
What it is used for
Preventing blood clots in the heart and brain. Pakistan’s leaflet lists more specific uses than the UK label.
| Source | Uses |
|---|---|
| Pakistan, Highnoon (Loprin) | Secondary prevention of cardiovascular disease; unstable angina and heart attack (NSTEMI and STEMI); suspected or confirmed transient ischaemic attack; ischaemic stroke not linked with atrial fibrillation, and acute ischaemic stroke; atrial fibrillation after a disabling stroke, before anticoagulants are considered; after a disabling stroke in people on anticoagulants for a prosthetic heart valve who are at significant risk of bleeding into the stroke (haemorrhagic transformation); and after coronary bypass surgery. |
| UK, aspirin 75 mg | Secondary prevention of thrombotic cerebrovascular or cardiovascular disease, and after bypass surgery. |
| NHS | At a low regular dose: to prevent blood clots, lower the chance of a heart attack or stroke, and prevent high blood pressure in pregnancy (pre-eclampsia). |
How to take it
Swallow the tablet whole with water, and don’t cut, chew or crush it, according to the UK product information for aspirin 75 mg gastro-resistant tablets (Dexcel); it is a gastro-resistant (enteric-coated) tablet.
- The dose depends on the condition, and the Pakistani leaflet’s regimens differ between them, so the choice belongs to your prescriber. Take it as they direct.
- How long: the NHS says low-dose aspirin to prevent a heart attack or stroke is usually taken for a long time, sometimes for life. Don’t stop it without asking your doctor.
- Antacids: the Pakistani leaflet says antacids reduce the effect of aspirin, and the UK patient leaflet says don’t take indigestion medicines immediately before or after it.
- Alcohol: the Pakistani leaflet says alcohol with aspirin increases the risk of stomach bleeding; the UK patient leaflet says don’t drink alcohol while taking it.
- Before an operation or a tooth extraction, tell the doctor or dentist you take it: the Pakistani leaflet says the risk of bleeding is higher, and stopping it for a while may be needed.
Who should not take it, or should ask a doctor first
From Highnoon’s Pakistani leaflet for Loprin unless another source is named.
- Must not take it: anyone with a stomach ulcer now or in the past, stomach or bowel bleeding, or other bleeding such as a bleed in the brain.
- Must not take it: anyone with a bleeding disorder such as haemophilia or a low platelet count, or who is already on an anticoagulant.
- Must not take it: anyone allergic to aspirin or other salicylates or NSAIDs, including some people with asthma in whom it can trigger an attack.
- Must not take it: anyone with gout, or severe liver or kidney disease. The leaflet says low-dose aspirin reduces uric acid excretion and can bring on gout attacks in people who tend to excrete less uric acid.
- Children under 16: must not take it except under medical supervision (Reye’s syndrome, above).
- Ask first: asthma, hay fever, nasal polyps or other chronic lung disease, which the leaflet names as risk factors for aspirin-triggered asthma attacks; high blood pressure; heavy periods, which it may make heavier; and older people, who are more likely to have stomach bleeding.
- Stop it at the first sign of a skin rash, mouth sores or any other sign of allergy: the leaflet says serious skin reactions have rarely been reported.
Other medicines
Anything else that thins the blood or irritates the stomach adds to aspirin’s bleeding risk.
| Medicine | What the source says | Source |
|---|---|---|
| Warfarin, heparin and other anticoagulants | What the source says: Increased risk of bleeding; the bleeding time should be monitored. Not recommended together unless strictly indicated. | Source: Pakistan |
| Clopidogrel, ticlopidine, dipyridamole; SSRI antidepressants such as sertraline and paroxetine | What the source says: Increased risk of stomach and gut bleeding. | Source: Pakistan |
| Other NSAID painkillers, and steroid tablets | What the source says: Increased risk of stomach ulcers and bleeding. | Source: Pakistan |
| Ibuprofen | What the source says: May block low-dose aspirin’s effect on platelets when taken at the same time. | Source: Pakistan |
| Methotrexate above 15 mg a week | What the source says: Must not be taken with aspirin. | Source: Pakistan; UK, 4.3 |
| Probenecid, sulfinpyrazone (for gout) | What the source says: Aspirin reverses their effect; avoid the combination. | Source: Pakistan; UK, 4.5 |
| Diabetes medicines (sulphonylureas, insulin), diuretics and blood pressure medicines, digoxin, lithium, valproate, phenytoin | What the source says: Listed by the leaflet as interacting: tell your doctor if you take any of them. | Source: Pakistan |
Pregnancy, pre-eclampsia and breastfeeding
Low-dose aspirin is sometimes prescribed in pregnancy, but only under a doctor’s supervision, and higher doses must not be used in the last three months.
| Who | What the sources say |
|---|---|
| Last three months of pregnancy | Pakistan: doses of 100 mg a day and higher must not be used, because they may harm the baby’s heart, lungs and kidneys, and prolong bleeding and labour. That rules out Loprin 150 mg. UK: doses up to 100 mg a day may only be used under strict obstetric monitoring. |
| Earlier in pregnancy | Pakistan: doses up to 100 mg a day for restricted obstetric use, with specialised monitoring, appear safe; above that, aspirin should not be given in the first and second trimesters unless clearly necessary. |
| Pre-eclampsia | NHS: your doctor may recommend low-dose aspirin from 12 weeks of pregnancy to prevent pre-eclampsia. NICE (UK): for this use, aspirin must be prescribed. The Pakistani leaflet does not mention pre-eclampsia. Never start aspirin in pregnancy on your own. |
| Breastfeeding | Pakistan: lists breastfeeding as a reason not to take it, yet its own breastfeeding section says short-term use doesn’t require stopping breastfeeding, while long-term or higher-dose use does. NHS: check with your doctor, who may recommend it if the benefits outweigh the risks to your baby. |
Side effects
Bleeding more easily and indigestion are the common ones, according to the UK product information for aspirin 75 mg gastro-resistant tablets (Dexcel).
| Source | Side effects |
|---|---|
| Pakistan | Indigestion, nausea, vomiting, stomach irritation; dizziness, ringing in the ears, headache; heavy periods. |
| Serious (Pakistan and UK) | Stomach or gut ulcers and bleeding (vomiting blood, black stools); bleeding in the brain; severe allergic reactions and asthma attacks; severe skin reactions (Stevens-Johnson syndrome). |
Driving: the UK label says aspirin does not usually affect driving or using machines. The Pakistani leaflet has no driving section.
Checking your pack is genuine
As of 23 October 2026, a search of DRAP’s website found no alert, recall or rapid alert naming Loprin.
- Check that the batch number on the carton matches the batch number on the blister inside, and that the pack is sealed.
- The genuine carton reads Loprin, aspirin, 30 enteric-coated tablets, with Highnoon’s name. If a pack looks different from your last one, ask our pharmacist before taking it.
We buy only from authorised distributors, and check the batch and expiry on every item before it is packed.
Information as of 23 October 2026. DRAP publishes new alerts on dra.gov.pk.
Returns and replacements
Medicines and supplements can’t be returned once they have left our pharmacy.
- Returned medicine can never go back into saleable stock. That is a safety rule, not a commercial one.
- If an item arrives damaged or wrong, tell us on WhatsApp within 24 hours and we replace it. That is us fixing our mistake, not a return.
- Anything that arrives expired or within a month of expiry we replace or refund, your choice, with no time limit.
Frequently asked questions
What is Loprin Tablet 75mg used for?
Loprin is low-dose aspirin. Highnoon’s Pakistani leaflet lists preventing heart attacks and strokes in people with heart or circulation disease, angina and heart attack, transient ischaemic attack and stroke, and use after coronary bypass surgery. It is not a painkiller: the leaflet says 75 mg is not suitable for pain, fever or inflammation.
Why do doctors prescribe Loprin 75mg?
To stop blood platelets clumping into clots in people who have heart or circulation disease, or who have already had a heart attack, mini-stroke or stroke. The Pakistani leaflet says to consult your doctor about the benefits and risks before starting long-term aspirin.
Is it safe to take Loprin every day?
It is usually taken every day, long term, on a doctor’s advice: the NHS says low-dose aspirin to prevent a heart attack or stroke is usually taken for a long time, sometimes for life. The main risk is bleeding, especially from the stomach, so report any unusual bleeding to your doctor.
What is the best time to take Loprin?
Neither the Pakistani leaflet nor the UK label names a time of day. The UK label says swallow it whole with water, without cutting, chewing or crushing it. Take it at the time your doctor advises.
Do you need a prescription to buy Loprin Tablet 75mg?
Yes. Highnoon’s Pakistani leaflet says it is to be sold and used on the prescription of a registered medical practitioner only, in English and in Urdu.
Questions about Loprin Tablet 75mg and 150mg (Aspirin)?
Send your question on WhatsApp and a pharmacist will come back to you.
Written by the ePharmacyy pharmacy team.
Last checked against the sources below on
DRAP registration
- Loprin 75mg Tablets (014900), Highnoon Laboratories Ltd. DRAP’s registry shows: Reviewed, “Not Verified”.
- Loprin 150mg Tablet (013127), Highnoon Laboratories Ltd. DRAP’s registry shows: Reviewed, “Not Verified”.
DRAP publishes no definition of this verification flag, so we can’t tell you what it means. We searched DRAP’s website for “Loprin”, “aspirin”, “acetylsalicylic” and “Highnoon” on 23 October 2026 and found no alert naming Loprin; the aspirin results were recalls of a different company’s brand. When we tested it, the search did not find a word that appears only inside an alert’s attached PDF, so an alert that names a product only in its PDF may not show up. DRAP describes its registered products index as a provisional list that “cannot be used as a reference for any purpose”. Checked against the registry on .
Sources
- DRAP registered products: Loprin 75mg Tablets, registration 014900
- DRAP registered products: Loprin 150mg Tablet, registration 013127
- DRAP notified price index: Loprin 75 mg and 150 mg (effective 27 July 2026)
- Highnoon Laboratories: Loprin product page
- Highnoon Laboratories: Loprin (aspirin) 75mg and 150mg, Pakistani package insert (Item Code 14002521)
- emc (UK): Aspirin 75mg Gastro-Resistant Tablets, Dexcel, summary of product characteristics (revised 9 October 2026)
- emc (UK): Aspirin 75mg Gastro-Resistant Tablets, Dexcel, patient information leaflet (revised August 2026)
- NHS: Aspirin
- NICE (UK) guideline NG133: Hypertension in pregnancy, recommendations