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Dermovate Cream and Ointment 0.05% (Clobetasol Propionate)

GlaxoSmithKline Pakistan LimitedDRAP reg. 003100

Dermovate (clobetasol propionate 0.05% cream and ointment, by GSK Pakistan) is a very potent topical steroid for inflamed, itchy skin conditions that respond to steroids, such as psoriasis, lichen planus and discoid lupus, according to GSK Pakistan’s prescribing information for Dermovate. We dispense it on prescription.

We dispense this on prescription

We accept a prescription from any registered doctor in Pakistan.

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Same day or next day in Karachi, Lahore, Islamabad, Rawalpindi for orders confirmed before 6pm. Tracked courier, 2 to 4 working days everywhere else. Delivery Rs 250 in Rawalpindi and Islamabad, Rs 300 everywhere else, cash on delivery. Delivery details

Prices in PKR, checked 4 November 2026.

What Dermovate is

  • It is a very potent skin steroid: GSK Pakistan’s prescribing information classes it as very potent (group IV), and lists other skin conditions that do not respond to less potent steroids among its uses.
  • Dermovate-NN is a different product: DRAP’s registry record for Dermovate NN ointment lists neomycin and nystatin with the clobetasol. We do not sell it, and nothing on this page applies to it.
  • We found no Pakistani document that states Dermovate’s condition of sale: GSK Pakistan’s prescribing information has none. Dispensing it on prescription is our own policy.
  • DRAP notifies no price for Dermovate: its price index has no Dermovate entry, and DRAP’s registry gives no price figure (its approved-price field says only “As per SRO”).

Cream or ointment, with DRAP registration

From the label claims in DRAP’s registry; both are 0.05% clobetasol propionate.

Active ingredient in each Dermovate form, with DRAP registration
FormIngredientAmount
Cream (DRAP reg. 003100)Ingredient: Clobetasol propionateAmount: 0.05% w/w
Ointment (DRAP reg. 003139)Ingredient: Clobetasol propionateAmount: 0.05% w/w

GSK Pakistan’s prescribing information says ointments are especially suited to dry, thickened or scaly patches, and creams to moist or weeping skin.

DRAP registers each form only in a 20 g tube.

What it is used for

Steroid-responsive skin conditions; the UK label limits it to short courses for the more stubborn ones.

Uses of clobetasol propionate, by source
SourceUses
Pakistan, GSK (Dermovate)Inflamed, itchy steroid-responsive skin conditions in adults, the elderly and children over 1 year: psoriasis (not widespread plaque psoriasis), stubborn (recalcitrant) dermatoses, lichen planus, discoid lupus erythematosus, and other conditions that do not respond to less potent steroids.
UK, DermovateShort-term treatment only of the more resistant inflamed, itchy steroid-responsive skin conditions that have not responded to less potent steroids.

How to use it

Apply it thinly, once or twice a day, as your doctor directs: GSK Pakistan’s prescribing information for Dermovate says use only enough to cover the affected area, then reduce how often you use it, or change to a weaker steroid, once the skin improves.

  • Maximum: GSK Pakistan’s prescribing information says not more than 4 weeks of treatment and not more than 50 g a week. If the condition worsens or does not improve within 2 to 4 weeks, the treatment and diagnosis should be re-evaluated.
  • Face and children: GSK Pakistan’s prescribing information says limit use to only a few days; the UK product information for Dermovate says 5 days if possible, and no covering (occlusion) of the face or a child’s skin.
  • Stopping, in eczema: GSK Pakistan’s prescribing information says that for atopic dermatitis (eczema), treatment should be stopped gradually once the condition is under control, with a moisturiser continued, because stopping suddenly can bring it back.
  • Eyes: GSK Pakistan’s prescribing information says keep it out of the eyes when used on the eyelids, because repeated exposure might cause cataract and glaucoma.

Who must not use it, or should check first

The first three conditions below should not be treated with Dermovate, and the last two need extra care, according to GSK Pakistan’s prescribing information for Dermovate.

Who should not use clobetasol propionate, or should check first, by source
WhoWhat the sources say
Untreated skin infections, rosacea, acne, perioral dermatitisPakistan and UK: should not be treated with Dermovate.
Itching without inflammation, or itching around the anus or genitalsPakistan and UK: should not be treated with Dermovate.
Children under 1 yearPakistan and UK: contraindicated.
PsoriasisPakistan: use with caution, because rebound relapses, generalised pustular psoriasis and local or systemic toxicity have been reported.
Infection spreading during treatmentPakistan: the steroid should be stopped and an appropriate anti-infective given.

Side effects

Itching and burning are the common ones, according to GSK Pakistan’s prescribing information for Dermovate.

Side effects of clobetasol propionate, by source
SourceSide effects
Pakistan, GSK (common)Itching; local skin burning or pain.
Pakistan, GSK (uncommon)Skin thinning (atrophy), stretch marks (striae), small visible blood vessels (telangiectasia).
Pakistan, GSK (very rare)Suppression of the body’s own steroid production with Cushing’s features (such as a rounded face), slowed growth in children, raised blood sugar and blood pressure; cataract and glaucoma; opportunistic infection.
UK, DermovateAlso lists topical steroid withdrawal reactions after long use: redness that can spread beyond the treated area, burning or stinging, itch, peeling and oozing pustules.

Pregnancy and breastfeeding

Ask your doctor before using it if you are pregnant or breastfeeding.

Clobetasol propionate in pregnancy and breastfeeding, from GSK Pakistan’s prescribing information
WhoWhat GSK Pakistan’s prescribing information says
PregnancyUse only if the expected benefit to the mother outweighs the risk to the baby, in the smallest amount for the shortest time.
BreastfeedingDo not apply it to the breasts, so the baby cannot swallow it.

Checking your pack is genuine

As of 4 November 2026, a search of DRAP’s website found no alert, recall or rapid alert naming Dermovate or clobetasol.

  • Check the tube and carton: DRAP registers Dermovate cream and ointment only in 20 g tubes, made by GlaxoSmithKline Pakistan in Karachi; the batch and expiry should match.
  • Dermovate-NN is a different product, with neomycin and nystatin added; check which one your prescription names.
  • If anything looks wrong, do not use it. Send us a photo of the carton and tube on WhatsApp, and report it to DRAP.

We buy only from authorised distributors, and check the batch and expiry on every item before it is packed.

Information as of 4 November 2026. DRAP publishes new alerts on dra.gov.pk.

Returns and replacements

Medicines and supplements can’t be returned once they have left our pharmacy.

  • Returned medicine can never go back into saleable stock. That is a safety rule, not a commercial one.
  • If an item arrives damaged or wrong, tell us on WhatsApp within 24 hours and we replace it. That is us fixing our mistake, not a return.
  • Anything that arrives expired or within a month of expiry we replace or refund, your choice, with no time limit.

Our returns policy

Frequently asked questions

What is Dermovate cream used for?

Dermovate is clobetasol propionate, a very potent skin steroid. GSK Pakistan’s prescribing information lists inflamed, itchy steroid-responsive conditions such as psoriasis, lichen planus and discoid lupus, and others that don’t respond to weaker steroids.

How long can I use Dermovate?

GSK Pakistan’s prescribing information says not more than 4 weeks and not more than 50 g a week, and only a few days on the face. Use it only as your doctor directs.

Can I use Dermovate on my face?

Only if your doctor says so, and briefly: GSK Pakistan’s prescribing information says the face is more prone to skin thinning and use there should be limited to only a few days. GSK Pakistan’s prescribing information also says acne, rosacea and perioral dermatitis should not be treated with it.

What are the side effects of Dermovate?

GSK Pakistan’s prescribing information lists itching and burning as common, and skin thinning and stretch marks as uncommon. Used on large areas or for long, it can suppress the body’s own steroid production.

Is Dermovate the same as Dermovate-NN?

No. DRAP’s registry lists Dermovate as clobetasol propionate alone, and Dermovate NN ointment as clobetasol with neomycin and nystatin. They are different products.

What is the price of Dermovate in Pakistan?

DRAP notifies no maximum price for Dermovate: its price index has no Dermovate entry. Our price for the 20 g cream is shown above, and we confirm the ointment price on WhatsApp.

Can I use Dermovate in pregnancy?

Only if your doctor decides the benefit outweighs the risk. GSK Pakistan’s prescribing information says use the smallest amount for the shortest time, and while breastfeeding do not apply it to the breasts.

Dermovate cream uses in Urdu

ڈرموویٹ میں کلوبیٹاسول پروپیونیٹ ہے؛ جی ایس کے پاکستان کی معلومات کے مطابق یہ جلد کا بہت تیز اسٹیرائیڈ ہے جو سوزش اور خارش والی جلد کی بیماریوں، جیسے سورائسس، میں لگایا جاتا ہے۔ انہی معلومات کے مطابق اسے 4 ہفتوں سے زیادہ اور ہفتے میں 50 گرام سے زیادہ استعمال نہ کریں، چہرے پر صرف چند دن، اور ایک سال سے کم عمر بچوں پر بالکل نہیں۔

Do you need a prescription to buy Dermovate?

We dispense Dermovate on prescription. We found no Pakistani document that states its condition of sale, so this is our own policy; in the UK, the NHS says clobetasol is only available with a prescription.

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Questions about Dermovate Cream and Ointment 0.05% (Clobetasol Propionate)?

Send your question on WhatsApp and a pharmacist will come back to you.

WhatsApp OrderCall 0316 5534828

Written by the ePharmacyy pharmacy team.

Last checked against the sources below on

DRAP registration

  • Dermovate Cream (003100), GlaxoSmithKline Pakistan Limited. DRAP’s registry shows: Provisionally Active, “Not Verified”.
  • Dermovate Ointment (003139), GlaxoSmithKline Pakistan Limited. DRAP’s registry shows: Provisionally Active, “Not Verified”.
  • Dermovate NN Ointment (006230), GlaxoSmithKline Pakistan Limited. DRAP’s registry shows: Provisionally Active, “Not Verified”.

DRAP publishes no definition of this verification flag, so we can’t tell you what it means. We searched DRAP’s website for “Dermovate” and “clobetasol” on 4 November 2026 and found no alert naming Dermovate or clobetasol. When we tested it, the search did not find a word that appears only inside an alert’s attached PDF, so an alert that names a product only in its PDF may not show up. DRAP describes its registered products index as a provisional list that “cannot be used as a reference for any purpose”. Checked against the registry on .

Sources

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