Calamox Tablet 375mg, 625mg, 1g, Suspension and Drops (Co-amoxiclav)

Bosch Pharmaceuticals (Pvt) LtdDRAP reg. 021510

Prescription required

Bosch’s Pakistani leaflet says Calamox is to be sold on the prescription of a registered medical practitioner only, in English and in Urdu, so we dispense it on prescription.

In stock

Tablets 625mg, strip of 6Rs 232.86Tablets 375mg, strip of 6Rs 178.78Tablets 1g, strip of 6Rs 294.66

Order on WhatsApp

Same day or next day in Karachi, Lahore, Islamabad, Rawalpindi for orders confirmed before 6pm. Tracked courier, 2 to 4 working days everywhere else. Delivery Rs 250 in Rawalpindi and Islamabad, Rs 300 everywhere else, cash on delivery. Delivery details

Prices in PKR, checked 28 October 2026.

What Calamox is

Calamox (co-amoxiclav: amoxicillin with clavulanic acid) is a penicillin-type antibiotic for bacterial infections such as sinusitis, middle-ear infection, chest infections and pneumonia, bladder and kidney infections, skin and soft tissue infections including animal bites and severe dental abscess, and bone and joint infections, according to Bosch’s Pakistani leaflet for Calamox. The leaflet says it is to be sold on prescription only, so we dispense it on prescription.

Calamox is not plain amoxicillin: every form contains both amoxicillin and clavulanic acid, according to DRAP’s registry.
Made by Bosch Pharmaceuticals in Karachi: Bosch’s own product page lists Calamox as co-amoxiclav, an antibiotic of the penicillin group, in tablets, suspensions, drops and injections.
The NHS says antibiotics do not work for viral infections such as colds and flu, and most coughs.
DRAP controls Calamox’s prices: its price index sets Rs 244.36 for 6 tablets of 625 mg and Rs 309.22 for 6 of 1 g, effective 27 July 2026, and we charge less. DRAP’s registry still shows lower approved prices for those two packs (Rs 225.77 and Rs 285.69); the index is the later figure.

The strengths, and how much of each ingredient

The number on the pack is the two ingredients added together, and the ratio between them is not the same in every strength.

Amoxicillin and clavulanic acid in each Calamox strength, from DRAP’s registry
Form	Amoxicillin	Clavulanic acid	Ratio
Tablet 375 mg	Amoxicillin: 250 mg	Clavulanic acid: 125 mg	Ratio: 2:1
Tablet 625 mg	Amoxicillin: 500 mg	Clavulanic acid: 125 mg	Ratio: 4:1
Tablet 1 g	Amoxicillin: 875 mg	Clavulanic acid: 125 mg	Ratio: 7:1
Suspension 156.25 mg/5 ml	Amoxicillin: 125 mg per 5 ml	Clavulanic acid: 31.25 mg per 5 ml	Ratio: 4:1
DS suspension 312.5 mg/5 ml	Amoxicillin: 250 mg per 5 ml	Clavulanic acid: 62.5 mg per 5 ml	Ratio: 4:1
Duo suspension 457 mg/5 ml	Amoxicillin: 400 mg per 5 ml	Clavulanic acid: 57 mg per 5 ml	Ratio: 7:1
Drops 62.5 mg/ml	Amoxicillin: 50 mg per ml	Clavulanic acid: 12.5 mg per ml	Ratio: 4:1

Because the ratios differ, one strength can’t simply be swapped for another by counting milligrams. Your doctor chooses the strength.

What is in each form, with DRAP registration

From the label claims in DRAP’s registry. Amoxicillin is present as amoxicillin trihydrate and clavulanic acid as potassium clavulanate.

Active ingredients in each Calamox form, with DRAP registration
Form	Ingredients	Amount
Tablet 375 mg (DRAP reg. 021509)	Ingredients: Amoxicillin; clavulanic acid	Amount: 250 mg; 125 mg
Tablet 625 mg (DRAP reg. 021510)	Ingredients: Amoxicillin; clavulanic acid	Amount: 500 mg; 125 mg
Tablet 1 g (DRAP reg. 026198)	Ingredients: Amoxicillin; clavulanic acid	Amount: 875 mg; 125 mg
Suspension 156.25 mg/5 ml (DRAP reg. 022968)	Ingredients: Amoxicillin; clavulanic acid	Amount: 125 mg; 31.25 mg per 5 ml
DS suspension 312.5 mg/5 ml (DRAP reg. 022969)	Ingredients: Amoxicillin; clavulanic acid	Amount: 250 mg; 62.5 mg per 5 ml
Duo suspension 457 mg/5 ml (DRAP reg. 053118)	Ingredients: Amoxicillin; clavulanic acid	Amount: 400 mg; 57 mg per 5 ml
Drops 62.5 mg/ml (DRAP reg. 058393)	Ingredients: Amoxicillin; clavulanic acid	Amount: 50 mg; 12.5 mg per ml

The Pakistani leaflet says the preparation contains a penicillin.

What it is used for

Bacterial infections only. Pakistan’s leaflet and the UK label for the 625 mg tablet list the same infections.

Uses of co-amoxiclav, by source
Source	Uses
Pakistan, Bosch (Calamox)	Acute bacterial sinusitis; acute middle-ear infection (otitis media); flare-ups of chronic bronchitis; community-acquired pneumonia; cystitis; kidney infection (pyelonephritis); skin and soft tissue infections, in particular cellulitis, animal bites and severe dental abscess with spreading cellulitis; bone and joint infections, in particular osteomyelitis.
UK, Augmentin 625mg	The same eight infections.

How to take it

The dose depends on the product, body weight and kidney function, according to Bosch’s Pakistani leaflet for Calamox, so the choice belongs to your prescriber. Take it as they direct.

With food: the Pakistani leaflet says take it at the start of a meal, to reduce stomach upset and help absorption.
How long: the Pakistani leaflet says treatment should not be extended beyond 14 days without review.
Suspensions and drops, once made up: the Pakistani leaflet says store them in a refrigerator, don’t freeze them, and use them within 7 days. Ask our pharmacist to make them up if you’re unsure.
Drops: the Pakistani leaflet says give them by mouth with the doser supplied, with children dosed by body weight.

Who should not take it, or should ask a doctor first

Pakistan’s oral leaflet and the UK label differ on liver history, so both are shown.

Who should not take co-amoxiclav, by source
Who	What the sources say
Allergy to antibiotics	Pakistan and UK: must not be used with an allergy to any penicillin, or a history of a severe immediate allergic reaction, such as anaphylaxis, to another beta-lactam (a cephalosporin, carbapenem or monobactam).
Jaundice or liver problems with co-amoxiclav before	UK, and Bosch’s leaflet for the Calamox injection: must not be used. Bosch’s leaflet for the tablets, suspensions and drops doesn’t list this, but says to use it with caution where there is evidence of liver impairment. Tell your doctor about any past liver problem with an antibiotic.
Glandular fever (infectious mononucleosis)	UK: should be avoided if glandular fever is suspected, because a measles-like rash has been linked with amoxicillin in this condition.

Other medicines

From Bosch’s Pakistani leaflet for Calamox.

Medicines that interact with co-amoxiclav, with source
Medicine	What the source says	Source
Warfarin and other oral anticoagulants	What the source says: Listed as interacting; the doctor may need to check blood clotting.	Source: Pakistan
Methotrexate	What the source says: Penicillins may reduce its excretion, potentially increasing its toxicity.	Source: Pakistan
Probenecid	What the source says: Use together is not recommended.	Source: Pakistan
Allopurinol	What the source says: Can increase the likelihood of allergic skin reactions.	Source: Pakistan
Mycophenolate mofetil	What the source says: Listed as interacting: tell your doctor if you take it.	Source: Pakistan

Pregnancy and breastfeeding

Ask your doctor before taking it if you are pregnant or breastfeeding.

Co-amoxiclav in pregnancy and breastfeeding, by source
Who	What the sources say
Pregnancy	Pakistan: use should be avoided unless the doctor considers it essential. NHS: you can usually take co-amoxiclav if you’re pregnant and your doctor thinks you need it.
Breastfeeding	Pakistan: only after the doctor has weighed the benefits and risks. NHS: you can usually take it while breastfeeding, but check with a pharmacist or doctor first.

Side effects

Diarrhoea is very common, and feeling or being sick is common, according to Bosch’s Pakistani leaflet for Calamox.

Side effects of co-amoxiclav, by source
Source	Side effects
Pakistan	Diarrhoea (very common); nausea and vomiting (common).
UK patient leaflet (serious)	Inflammation of the large intestine, causing watery diarrhoea usually with blood and mucus, stomach pain and/or fever.
Pakistan (liver)	Liver problems, mostly in men and older people and with longer treatment; usually reversible, but they may be severe.

Driving: the Pakistani leaflet says side effects such as allergic reactions, dizziness and convulsions may affect the ability to drive and use machines.

Calamox injection

Calamox is also registered as 1.2 g (DRAP reg. 021508), 0.6 g (DRAP reg. 021507) and 0.3 g (DRAP reg. 057750) injections. Bosch’s leaflet for the injection says it is given slowly into a vein, by injection or infusion, and is not suitable for injection into a muscle.

We don’t sell the injection online: it is given in a clinic or hospital.

Checking your pack is genuine

DRAP has named one spurious batch of Calamox 1g tablets, C240712. If your pack’s batch number is C240712, do not take it.

Check that the batch number on the carton matches the batch number on the strip inside, and that the pack is sealed.
The genuine 625mg carton says Calamox (Co-amoxiclav) Tablets 625mg, 6 Tablets, with Bosch’s name. If a pack looks different from your last one, ask our pharmacist before taking it.
If anything looks wrong, do not take it. Send us a photo of the carton and strip on WhatsApp, and report it to DRAP.

DRAP Rapid Alert No. I/S/05-25-41, 13 May 2025: Calamox tablets 875mg/125mg (the 1g), batch C240712, purported to be made by Bosch Pharmaceuticals, declared spurious, as reported to DRAP by the Directorate of Drug Control Punjab.

We buy only from authorised distributors, and check the batch and expiry on every item before it is packed.

Information as of 28 October 2026. DRAP publishes new alerts on dra.gov.pk.

Returns and replacements

Medicines and supplements can’t be returned once they have left our pharmacy.

Returned medicine can never go back into saleable stock. That is a safety rule, not a commercial one.
If an item arrives damaged or wrong, tell us on WhatsApp within 24 hours and we replace it. That is us fixing our mistake, not a return.
Anything that arrives expired or within a month of expiry we replace or refund, your choice, with no time limit.

Our returns policy

Frequently asked questions

What is Calamox 625 used for?

Calamox is co-amoxiclav, an antibiotic. Bosch’s Pakistani leaflet lists infections such as sinusitis, middle-ear infection, chest infections and pneumonia, bladder and kidney infections, skin and soft tissue infections, and bone and joint infections. The NHS says antibiotics do not work for viral infections such as colds and flu.

Is Calamox Augmentin?

They are different brands of the same combination. Both are co-amoxiclav, amoxicillin with clavulanic acid: Calamox is made by Bosch Pharmaceuticals and Augmentin by GlaxoSmithKline Pakistan, and DRAP’s registry gives the 625 mg tablet of each 500 mg of amoxicillin and 125 mg of clavulanic acid. Don’t switch from one to the other without asking your doctor or pharmacist, and keep to the same strength.

Is Calamox the same as amoxicillin?

No. Calamox contains clavulanic acid as well as amoxicillin, according to DRAP’s registry; plain amoxicillin products contain amoxicillin alone.

Should Calamox be taken with food?

Yes. Bosch’s Pakistani leaflet says take it at the start of a meal, to reduce stomach upset and help absorption.

Do you need a prescription to buy Calamox?

Yes. Bosch’s Pakistani leaflet says it is to be sold on the prescription of a registered medical practitioner only, in English and in Urdu.

Questions about Calamox Tablet 375mg, 625mg, 1g, Suspension and Drops (Co-amoxiclav)?

Send your question on WhatsApp and a pharmacist will come back to you.

WhatsApp Order Call 0316 5534828

Written by the ePharmacyy pharmacy team.

Last checked against the sources below on 28 October 2026

DRAP registration

Calamox Tablets 625mg (021510), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: In Process, “Partially Verified”.
Calamox Tablets 375mg (021509), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Calamox Tablets 1g (026198), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Reviewed, “In Process”.
Calamox Suspension 156.25mg/5ml (022968), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Calamox DS Suspension 312.5mg/5ml (022969), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Calamox-Duo Suspension 457mg/5mL (053118), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Calamox Drop (058393), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Calamox 1.2g Injection (021508), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Calamox Injection 600mg (021507), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Reviewed, “Not Verified”.
Calamox 300mg Injection (057750), Bosch Pharmaceuticals (Pvt) Ltd. DRAP’s registry shows: Provisionally Active, “Not Verified”.
Augmentin 625mg Tablet (017297), GlaxoSmithKline Pakistan Limited. DRAP’s registry shows: Reviewed, “Not Verified”.

DRAP publishes no definition of this verification flag, so we can’t tell you what it means. We searched DRAP’s website for “Calamox”, “co-amoxiclav” and “Bosch” on 28 October 2026 and found one alert naming a spurious batch of Calamox 1g tablets, C240712 (below); the other Bosch alerts concerned other products. When we tested it, the search did not find a word that appears only inside an alert’s attached PDF, so an alert that names a product only in its PDF may not show up. DRAP describes its registered products index as a provisional list that “cannot be used as a reference for any purpose”. Checked against the registry on 28 October 2026.